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Pediatric Non-Hodgkin Lymphoma

What is non-Hodgkin lymphoma (NHL)?

NHL is cancer in the lymphatic system. The lymphatic system is part of the immune system and functions to fight disease and infections.

The lymphatic system includes the following:

  • Lymph fluid. Fluid containing lymphocyte cells.

  • Lymph vessels. Thin tubes that carry lymph fluid throughout the body.

  • Lymphocytes. Specific white blood cells that fight infections and disease.

  • Lymph nodes. Bean-sized organs, found in the underarm, groin, neck, chest, abdomen and other parts of the body, that act as filters for the lymph fluid as it circulates through the body.

NHL causes the cells in the lymphatic system to abnormally reproduce, eventually causing tumors to grow. The cells can also spread to other organs and tissues in the body.

Lymphomas (including both Hodgkin and non-Hodgkin lymphomas) are the third most common childhood cancer in the U.S. About 800 cases of NHL are diagnosed in children and teens in the U.S. each year. They can occur at any age from infancy to adulthood.

NHL affects males more often than females, and is more common among white children than among African-American children and children of other races.

Staging and classification of non-Hodgkin lymphoma is based on the extent of the disease and the specific cells involved.




Treatment Services

Cancer Surgery

Our expert surgical oncology team provides the full spectrum of surgical treatment for children with cancer.


Chemotherapy is the use of anticancer drugs to treat cancer cells. Learn more about this treatment.


Radiation therapy (also called radiation oncology) uses special kinds of energy waves or particles to fight cancer. Learn more about this treatment.

Children's Team

Children's Team


Locations that Treat this Condition

Locations that Treat this Condition

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Leukemia Lymphoma Program

We deliver comprehensive care for all blood cancers including chemotherapy, bone marrow transplant and experimental therapeutics.


Our oncology (cancer) team provides personalized treatment plans for children with cancer, including access to clinical trials.

Blood and Marrow Transplant

Our blood and bone marrow disease experts provide advanced transplant procedures for children and teenagers.

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