Brian R. Rood, MD, is an Associate Professor of Pediatrics in the Center for Cancer and Blood Disorders at Children’s National Health System whose primary clinical focus is pediatric neuro-oncology. Dr. Rood joined the faculty of Children’s National in 2002 after completing a fellowship in Pediatric Hematology/Oncology as well as a research fellowship in the molecular biology of brain tumors, both at Children’s National and Children’s Research Institute.
Dr. Rood is the Director of Clinical Neuro-Oncology at Children’s and cares for brain tumor patients on the inpatient oncology ward and in the outpatient clinic. He is co-principal investigator with Roger Packer, MD, of the Pediatric Brain Tumor Consortium clinical trial program at Children’s National and runs an active molecular biology lab in the Center for Cancer and Immunology Research. He also is investigating the proteome of medulloblastoma, the most common malignant brain tumor of childhood, in order to determine the differences between the four subgroups of the disease in an effort to identify therapeutic targets. He aims to further this work by identifying medulloblastoma specific proteins in the cerebrospinal fluid in order to discover biomarkers capable of providing insight into the biology of brain tumors and detecting recurrent disease. Dr. Rood also is working to identify microsatellite markers in a person’s DNA that predict the risk of developing different kinds of brain tumors.
Dr. Rood has two children. His favorite past times include designing and building furniture, sailing, reading, and playing the mandolin.
Research & Publications
Research & Publications
Somatic Intronic Microsatellite Loci Differentiate Glioblastoma from Lower-Grade Gliomas
Deciphering HIC1 control pathways to reveal new avenues in cancer therapeutics
(2013) Expert Opinion on Therapeutic Targets
Durable response of intracranial cellular hemangioma to bevacizumab and temozolomide
(2013) Journal of Neurosurgery Pediatrics
Proteomic Profiling of Cerebrospinal Fluid Identifies Prostaglandi D2 Synthase as a Putative Biomarker for Pediatric Medulloblastoma: A Pediatric Brain Tumor Consortium Study
Scavenger chemokine (CXC motif) receptor 7 (CXCR7) is a direct target gene of HIC1
(2009) Journal of Biological Chemistry
View publications on PubMed