Skip to main content Skip to navigation
We care about your privacy. Read about your rights and how we protect your data. Get Details

Education & Training

  • Fellowship, Pediatric Cardiology, 1995
    Children's Hospital of Philadelphia
  • Residency, Pediatrics, 1992
    Cornell New York Hospital
  • Internship, Pediatrics, 1990
    Cornell New York Hospital
  • MD, 1989
    Icahn School of Medicine at Mount Sinai
  • BA, 1985
    Johns Hopkins University

Board Certifications

  • American Board of Pediatrics/Pediatric Cardiology

Awards & Recognition

  • Top Doctors Washingtonian (2019)
  • Top Doctors No Va Magazine (2023, 2022, 2021)

National Provider ID: 1386704633


Mary Donofrio, M.D., is a national expert in prenatal cardiology and has published over 130 papers, including the American Heart Association Scientific Statement on the Diagnosis and Treatment of Fetal Cardiac Disease. She is one of the founders and current president of the Fetal Heart Society, a non-profit organization created to advance the art and science of prenatal cardiovascular medicine, improve the understanding of in-utero cardiovascular physiology by fostering scientific research, organized research collaboration and mentorship, and educate medical and research professionals through scientific publications, education and meetings.

Research & Publications

Chelliah A, Moon-Grady AJ, Peyvandi S, Chiu JS, Bost JE, Schidlow D, Carroll SJ, Davey B, Divanovic A, Hornberger L, Howley LW, Kavanaugh-McHugh A, Kovalchin JP, Levasseur SM, Lindblade CL, Morris SA, Ngwezi D, Pruetz JD, Puchalski MD, Rychik J, Samai C, Tacy TA, Tworetzky W, Vernon MM, Yeh J, Donofrio MT. Contemporary Outcomes in Tetralogy of Fallot With Absent Pulmonary Valve After Fetal Diagnosis. J Am Heart Assoc. 2021 Jun 15;10(12):e019713. doi: 10.1161/JAHA.120.019713. Epub 2021 Jun 8. PubMed PMID: 34098741; PubMed Central PMCID: PMC8477871.

Krishnan A, Jacobs MB, Morris SA, Peyvandi S, Bhat AH, Chelliah A, Chiu JS, Cuneo BF, Freire G, Hornberger LK, Howley L, Husain N, Ikemba C, Kavanaugh-McHugh A, Kutty S, Lee C, Lopez KN, McBrien A, Michelfelder EC, Pinto NM, Schwartz R, Stern KWD, Taylor C, Thakur V, Tworetzky W, Wittlieb-Weber C, Woldu K, Donofrio MT. Impact of Socioeconomic Status, Race and Ethnicity, and Geography on Prenatal Detection of Hypoplastic Left Heart Syndrome and Transposition of the Great Arteries. Circulation. 2021 May 25;143(21):2049-2060. doi: 10.1161/CIRCULATIONAHA.120.053062. Epub 2021 May 17. PubMed PMID: 33993718; PubMed Central PMCID: PMC8162295.

Altman CA, Donofrio MT, Arya B, Wasserman M, Ensing GJ, Cohen MS, Lewin MB, Swaminathan M, Barker PCA. ASE Statement on Adapting Pediatric, Fetal, and Congenital Heart Disease Echocardiographic Services to the Evolving COVID-19 Pandemic. J Am Soc Echocardiogr. 2021 May;34(5):553-561. doi: 10.1016/j.echo.2021.01.012. Epub 2021 Jan 28. PubMed PMID: 33516940; PubMed Central PMCID: PMC7842196.

Sethi N, Klugman D, Said M, Hom L, Bowers S, Berger JT, Wernovsky G, Donofrio MT. Standardized delivery room management for neonates with a prenatal diagnosis of congenital heart disease: A model for improving interdisciplinary delivery room care. J Neonatal Perinatal Med. 2021;14(3):317-329. doi: 10.3233/NPM-200626. Review. PubMed PMID: 33361613.

Peyvandi S, Donofrio MT. Circulatory Changes and Cerebral Blood Flow and Oxygenation During Transition in Newborns With Congenital Heart Disease. Semin Pediatr Neurol. 2018 Dec;28:38-47. doi: 10.1016/j.spen.2018.05.005. Epub 2018 Jun 20. Review. PubMed PMID: 30522727.

Schidlow DN, Donofrio MT. Prenatal Maternal Hyperoxygenation Testing and Implications for Critical Care Delivery Planning among Fetuses with Congenital Heart Disease: Early Experience. Am J Perinatol. 2018 Jan;35(1):16-23. doi: 10.1055/s-0037-1603991. Epub 2017 Jul 26. PubMed PMID: 28746973.

Sanz JH, Berl MM, Armour AC, Wang J, Cheng YI, Donofrio MT. Prevalence and pattern of executive dysfunction in school age children with congenital heart disease. Congenit Heart Dis. 2017 Mar;12(2):202-209. doi: 10.1111/chd.12427. Epub 2016 Nov 11. PubMed PMID: 27863079; PubMed Central PMCID: PMC5383529.

Donofrio MT, Skurow-Todd K, Berger JT, McCarter R, Fulgium A, Krishnan A, Sable CA. Risk-stratified postnatal care of newborns with congenital heart disease determined by fetal echocardiography. J Am Soc Echocardiogr. 2015 Nov;28(11):1339-49. doi: 10.1016/j.echo.2015.07.005. Epub 2015 Aug 20. PubMed PMID: 26298099.

Donofrio MT, Moon-Grady AJ, Hornberger LK, Copel JA, Sklansky MS, Abuhamad A, Cuneo BF, Huhta JC, Jonas RA, Krishnan A, Lacey S, Lee W, Michelfelder EC Sr, Rempel GR, Silverman NH, Spray TL, Strasburger JF, Tworetzky W, Rychik J. Diagnosis and treatment of fetal cardiac disease: a scientific statement from the American Heart Association. Circulation. 2014 May 27;129(21):2183-242. doi: 10.1161/01.cir.0000437597.44550.5d. Epub 2014 Apr 24. Review. PubMed PMID: 24763516.

Donofrio MT, Levy RJ, Schuette JJ, Skurow-Todd K, Sten MB, Stallings C, Pike JI, Krishnan A, Ratnayaka K, Sinha P, duPlessis AJ, Downing DS, Fries MI, Berger JT. Specialized delivery room planning for fetuses with critical congenital heart disease. Am J Cardiol. 2013 Mar 1;111(5):737-47. doi: 10.1016/j.amjcard.2012.11.029. Epub 2013 Jan 2. PubMed PMID: 23291087.