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Hydronephrosis Referral Guidelines
Hydronephrosis refers to when the kidneys are abnormally dilated or overfilled with urine. There are several causes, many of which do not cause any harm to the kidneys, but in some cases Hydronephrosis can be associated with poorly functioning kidneys. Hydronephrosis can affect one (unilateral) or both (bilateral) kidneys, and it resolves on its own in about half of all cases.
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- Fetal: Hydronephrosis can be detected during a routine prenatal ultrasound in the second trimester. You may be referred to our Fetal Medicine Institute for a high-resolution (level II) ultrasound and MRI scans to evaluation your baby’s condition.
- The Fetal Medicine Institute at Children’s National may recommend further testing after the baby is born. Testing may include
- X-ray of the bladder to check for vesicoureteral reflux
- Diagnostic imaging of the kidneys to assess function and proper urine drainage
- Newborns: Newborns and infants with hydronephrosis usually show few or no symptoms at all. Older children who have moderate to severe cases may experience:
- Pain in the side or abdomen
- Intermittent nausea and vomiting, particularly in the afternoons and early evenings, which spontaneously improve by the next morning and which is not also associated with fever
- Blood in the urine
- Children: Older children may be more likely to get urinary tract infections (UTI), in which symptoms include:
- Persistent feeling of needing to urinate
- Pain in the lower abdomen during urination
- Cloudy or bloody urine
- Back or side pain
- Fever
- Vomiting
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- Mild unilateral hydronephrosis / pyelectasis (SFU Grade 1 or 2)
- If initially seen on DOL 1-5, repeat sonogram in 3 months:
- If improved, no further studies
- If stable, repeat in 6-9 months
- If worsened, refer to pediatric urologist
- If initially seen on sonogram after DOL 1-5:
- Repeat in 6-9 months
- If stable, no further studies
- If worsened, refer to pediatric urologist
- If associated with duplication of collecting system or bilateral
- Refer to pediatric urologist, recommend starting antibiotic prophylaxis with amoxicillin 25 mg/kg/dy until further evaluation is completed
- Moderate or several unilateral hydronephrosis (SFU Grade 3 or 4)
- Refer to pediatric urologist; recommend starting antibiotic prophylaxis with amoxicillin 25 mg/kg/dy until further evaluation is completed

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The physician referral line is 202-476-2670
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- The parent should bring the following to their appointment:
- Prenatal and postnatal imaging, films or CD (postnatal sonogram at 2-3 weeks of age)
- Prenatal and postnatal sonogram films or CD, lab work
Outpatient Appointment Referral Pads (PDFs)
Northern Virginia - 2021: English | En Español
Maryland - 2021: English | En Español
Montgomery County Imaging - 2020: English
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