About the Lab
We are a neuroscience lab that studies how brain circuits are shaped by experience and how these circuits are disrupted in neurodevelopmental disorders.
We seek to advance basic knowledge and to improve the lives of individuals with neurodevelopmental disorders through a collaborative program of basic and translational research.
Visual sequences drive experience-dependent plasticity in mouse anterior cingulate cortexSidorov MS, Kim H, Rougie M, Williams B, Siegel JJ, Gavornik JP, and Philpot BD. Cell Reports 32(11): 109152 (2020)
Abnormal coherence and sleep composition in children with Angelman syndrome: a retrospective EEG studyden Bakker H*, Sidorov MS*, Lee DJ, Fan Z, Bird LM, Chu CJ, and Philpot BD Molecular Autism 9:32 (2018)
Enhanced operant extinction and prefrontal excitability in a mouse model of Angelman syndromeSidorov MS, Judson MC, Kim H, Rougie M, Ferrer AI, Nikolova VD, Riddick NV, Moy SS, and Philpot BD Journal of Neuroscience 38(11): 2671-2682 (2018)
Delta rhythmicity is a reliable EEG biomarker in Angelman syndrome: a parallel mouse and human analysisSidorov MS, Deck GM, Dolatshahi M, Bird LM, Thibert RL, Chu CJ, and Philpot BD Journal of Neurodevelopmental Disorders 9:17. (2017)
GABAergic neuron-specific loss of Ube3a causes Angelman syndrome-like EEG abnormalities and enhances seizure susceptibilityJudson MC*, Wallace ML*, Sidorov MS, Burette AC, Gu B, Van Woerden GM, King IF, Han JE, Zylka MJ, Elgersma Y, Weinberg RJ, and Philpot BD Neuron 90: 56-69 (2016)