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Abraham Laboratory

About the Lab

The Abraham Laboratory has a primary aim of advancing curative therapies for sickle cell disease such as allogeneic hematopoietic stem cell transplantation and autologous hematopoietic stem cell gene therapy approaches. The lab focuses on the immunobiology of hematopoietic cell engraftment, virus-specific immunity restoration following transplantation, and identifying the best hematopoietic stem cell source for gene modification to treat patients during early childhood prior to the development of irreversible complications of sickle cell disease.