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Radiation‐Free Quantification of Intracranial Volume and Head Malformations from 3D Photography


Researchers at Children's National Hospital have developed a non-invasive, radiation-free surgical software framework that analyzes three-dimensional photography and provides clinical important measurements in terms of intracranial volume and head shape malformations.


Head volume correlates with brain pathologies. Intracranial volume (ICV) enables the study of brain development, craniofacial pathologies, determine course of treatment and evaluate surgical outcome. ICV and cranial shape are evaluated using CT and MR imaging. However, these imaging modalities require radiation which typically involves sedation. 3D photography is a non-invasive, radiation-free and anesthesia-free avenue that can be used, however there are no techniques currently available to do cranial measurements using this method. Inventors utilize 3D photography and imaging data to provide a robust quantitative framework for these cranial measurements as a way of studying and monitoring brain development and abnormalities. The following are advantages of this technology:

  1. Reduces exposure to unnecessary radiation.
  2. Low prediction error and high accuracy.
  3. Non-Invasive.
  4. Cost-effective due to fewer radiation procedures required.


  • Brain Development Evaluation and Treatment Prognosis

Stage of Development

  • Validated pre-clinical data acquired.

Intellectual Property Status

  • Software Available

This technology is available for exclusive or non-exclusive licensing.

Licensing Contact