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The Children's National Research Institute

CRI Bioinformatics Unit

Exiting DNA

The CRI Bioinformatics Unit (CBU) provides bioinformatics consultation and analytical services in an initiative sponsored by the Center for Genetic Medicine Research, the Center for Translational Research, the Clinical and Translational Institute at Children’s National (CTSI-CN), the District of Columbia Intellectual and Developmental Disabilities Research Center (DC-IDDRC) and the Chief Research Officer’s office at Children’s National.


We assist in the following experimental design consultation, grant technical writing support and data analysis.

Data analysis includes:

  • RNA sequencing
    • Differential gene expression
    • Single nucleotide variation detection
    • Fusion analysis
  • Whole genome sequencing
    • De novo assembly
    • Single nucleotide variation detection
    • Copy number variation
    • Structural variant detection
  • Exome sequencing
    • Single nucleotide variation detection
    • Copy number variation
    • Structural variant detection
  • Microbiome analysis (16s and metagenomics)
  • Single cell sequencing
  • T-cell receptor sequencing
  • Methylation sequencing (bisulphite sequencing)
  • Chip sequencing
  • Microarray
  • Other/custom analysis

The CBU also actively participates in training the next generation of biomedical researchers with the goal of enabling quality research and education through seminars and workshops.

To initiate a project with the Bioinformatics Unit, please fill out the submission form to share details of your experiment and schedule a consultation.

Preliminary data processing and analysis turnaround time is typically 2-3 weeks depending upon experiment and number of samples. Complex downstream data analysis may take more time. Completion timelines will be discussed during the consultation.

If you need more information about data submission or the CRI Bioinformatics Unit, please contact us at