The Children's Research Institute
Jason Triplett, Ph.D., Laboratory
Integrating sensory information
We experience the world using multiple senses, each of which is initially processed separately and then bound together in associative areas of the brain to create a unified percept. Our lab is focused on understanding the developmental mechanisms by which sensory information is brought together in the brain. Specifically, in the visual, somatosensory, and auditory systems, neurons are organized into topographic maps in which neighboring monitor adjacent regions of space. In associative centers, these maps must be brought into register in order to integrate sensory information. We use a wide range of techniques, including anatomical tracing and in vivo electrophysiology, in transgenic mouse models to understand this complex problem.