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The Children's Research Institute

Developing Brain Research Laboratory

The Developing Brain Research Laboratory, directed by Catherine Limperopoulos, Ph.D., is housed in the Division of Diagnostic Imaging and Radiology and affiliated with the Fetal and Transitional Medicine Program at Children’s National Hospital. Our research focuses on the developing brain, both in utero and in the newborn stages of life. We are developing advanced MRI (magnetic resonance imaging) techniques to examine the structure, connectivity, and metabolism of the brain in ways that cannot be done with conventional MRI studies. It is our long-term goal to be able to identify babies with impaired brain growth as soon as possible, so that the proper interventions and clinical planning can take place.

Faculty members

Research studies

  • Fetal Brain Study: Healthy Starts for Tiny Hearts
  • Quantifying Brain Development with MRI

Placenta studies

  • In Vivo fMRI
  • Advanced MRI is needed to identify early markers of impaired placental structure and function in the high-risk pregnancy
  • Preemie Study: Cerebellar Development in the Preterm Infant (CRIB)
  • ONESIE Study: Vulnerable Preterm Cerebellum
  • MAGIC Study: Preterm Brain Studies In Vivo
  • Cerebellar development in the preterm infant

Previous studies

  • Brain development in the fetus with congenital heart disease – The ABC Study