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The Children's National Research Institute

The Neonatal and Infant Airway Biology Laboratory (Gustavo Nino, M.D., MSHS, D'ABSM Laboratory)

About Our Lab

The Neonatal and Infant Airway Biology Laboratory at Children's National was developed to advance our knowledge of the pathobiology of respiratory disorders in young children, the number one cause of hospitalization and mortality in this age group worldwide. We are particularly interested in understanding why humans are highly susceptible to respiratory viruses during early life. To address this question, we employ a variety of state-of-the-art techniques for respiratory phenotyping including age-appropriate multi-language scales and computer-based analysis of lung imaging and neonatal bedside monitors.

We also interrogate molecular mechanisms driving respiratory phenotypes using a human model of the airway epithelium of newborns and infants, which was developed in our lab applying cutting-edge conditional reprogramming cell technology.

There are three major lines of research in our lab:

  1. Developmental immunology of the human airway epithelium
  2. Pathobiology of respiratory disorders in infants born prematurely
  3. Novel tools for respiratory phenotyping in young children


Principal Investigator

Gustavo Nino Barrera

Gustavo Nino, M.D., MSHS, D'ABSM

Principal Investigator, Airway Biology Research at the Center for Genetic Medicine Research Genomics and Precision Medicine

Pediatric Pulmonary Attending Physician

Research Profile