The Children's Research Institute
The Hahn Lab studies the impact of antibiotics on microbial diversity within the airway microbiome of children with cystic fibrosis. We seek to understand how antibiotic pharmacokinetics and antibiotic resistance affect the balance of bacteria within the airways, and how information about the airway microbiome could be used to improve antibiotic prescribing.
Focus of this lab: Drosophila Models of heart, kidney and blood diseases
Duchenne muscular dystrophy (DMD) is a severe and relentlessly progressive myopathy which results from out-of-frame or nonsense mutations in the X-linked DMD gene that disrupt the mRNA open reading frame and prevent translation of dystrophin protein.