The Children's Research Institute
Our clinical research programs investigate diseases in a wide range of health topics and lead the field in national clinical trials.
Our behavioral research addresses child and caregiver psychosocial functioning related to acute and chronic illnesses. This includes the factors that affect disease self-management, adherence and quality of life; the direct and indirect effects of diseases and medical treatments on cognitive, behavioral, emotional and social outcomes; and the development of interventions designed to promote adaptive coping and adjustment, adherence and better health.
Our Neuro-Oncology Research Program focuses on brain tumors, while our center's Medulloblastoma Special Interest Group seeks to understand the causative mechanism and improving the treatment of medulloblastoma, which is a cancerous tumor that starts in the region of the brain at the base of the skull.
Our cancer biology and experimental cancer therapy research includes a focus on brain tumor biomarkers, neurofibromatosis and pleuropulmonary blastoma.
This program includes research into targeting pathogens, eliminating cancer and bone marrow transplantation. Included in our work is the Cellular Therapy Laboratory and the CETI laboratory at the George Washington University.
Among the groups related to our clinical oncology research are the Pediatric Brain Tumor and Children's Brain Tumor Tissue consortiums, COllaborative Network for NEuro-oncology Trials, National Pediatric Cancer Foundation, Children's Oncology Group and Investigational Lead Early Phase Trials.
Our research into blood disorders, known as hematology, involves the study of sickle cell disease and bleeding disorders and coagulopathy.
Program faculty members are engaged in various research protocols related to food allergy, including clinical trials of peanut oral immunotherapy and translational research on the role of B cells and regulatory B cells on the development of food allergy, sensitization and tolerance.
Our pathology and laboratory medicine research focuses on technological advancement of testing and diagnosis. We also investigate the pathological basis of disease.