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The Children's National Research Institute

Research Programs

Our clinical research programs investigate diseases in a wide range of health topics and lead the field in national clinical trials.

Behavioral Research

Our behavioral research addresses child and caregiver psychosocial functioning related to acute and chronic illnesses. This includes the factors that affect disease self-management, adherence and quality of life; the direct and indirect effects of diseases and medical treatments on cognitive, behavioral, emotional and social outcomes; and the development of interventions designed to promote adaptive coping and adjustment, adherence and better health.

Blood Disorders

Our research into blood disorders, known as hematology, involves the study of sickle cell disease and bleeding disorders and coagulopathy.

Immunology Immunodeficiency

Our immunology research includes a joint clinical research program that includes our Division of Allergy and Immunology and our Infectious Disease program.

Clinical Oncology

Among the groups related to our clinical oncology research are the Pediatric Brain Tumor and Children's Brain Tumor Tissue consortiums, COllaborative Network for NEuro-oncology Trials, National Pediatric Cancer Foundation, Children's Oncology Group and Investigational Lead Early Phase Trials.

Brian R. Rood, M.D., director of Clinical Neuro-Oncology at Children's National, holds a small cylinder with his blue-gloved hands toward a square container while sitting in a laboratory.

Neuro-Oncology Research

Our Neuro-Oncology Research Program focuses on brain tumors, while our center's Medulloblastoma Special Interest Group seeks to understand the causative mechanism and improving the treatment of medulloblastoma, which is a cancerous tumor that starts in the region of the brain at the base of the skull.

Food Allergy Program

Program faculty members are engaged in various research protocols related to food allergy, including clinical trials of peanut oral immunotherapy and translational research on the role of B cells and regulatory B cells on the development of food allergy, sensitization and tolerance.

Pathology and Laboratory Medicine

Our pathology and laboratory medicine research focuses on technological advancement of testing and diagnosis. We also investigate the pathological basis of disease.