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The Children's Research Institute

Diffuse Intrinsic Pontine Glioma (DIPG) Research

Dr Nazarian in lab




Dr. Javad Nazarian leads a team of researchers dedicated to learning more about Diffuse Intrinsic Pontine Glioma (DIPG). Watch the video to learn more.

Learn More

For 45 years, clinicians around the nation have been offering the parents of pediatric patients diagnosed with diffuse intrinsic pontine glioma (DIPG) the same grim prognosis. Now, researchers at Children’s National are seizing the opportunity to change that narrative, by exploring the genetic mutations associated with this disease to unlock the possibility of new therapies. These discoveries and new-found knowledge come as a direct result of parents donating specimens, judicious shepherding of resources by researchers, development of pre-clinical models, and support from families and small foundations.

Key to this work is multidisciplinary  collaboration across divisions and departments. Each member of the DIPG team, including neurosurgery, oncology, immunology, genomics and proteomics, brings insight and unique perspective to the rest of the team, accelerating the pace of research discoveries being translated into clinical care.

Our Team

Led by Dr. Javad Nazarian, our multidisciplinary DIPG team includes expert clinicians and researchers poised to significantly advance our understanding and treatment of DIPG.

Meet Our Team

Clinical Trials

Children’s is currently leading a study of DIPG tumor mutations and is involved in several national, multi-center clinical trials of promising solutions.


Current & Future Trials

Support DIPG research

Thanks to philanthropic support, our multidisciplinary team of experts have been able to generate the complete protein profile of CSF from children with brain tumors.  

Donate now

Diffuse Intrinsic Pontine Glioma (DIPG) Research Team