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The Children's National Research Institute

Research Profile

Research Interests

  • Epilepsy Research
  • Intellectual and Developmental Disabilities 

Education & Training

  • Fellowship, Epilepsy, Clinical Neurophysiology & Neuroimaging, Clinical Epilepsy Section, National Institute of Neurological Disorders at the National Institutes of Health, Washington, DC, (1990-1993)
  • Residency (Chief Resident, 1988-1990), Pediatric Neurology, John Hopkins Hospital, Baltimore, MD, (1987-1990)
  • Internship & Residency, Pediatrics, Children's Hospital of Pittsburgh, Pittsburgh, PA, (1985-1987)
  • M.D., Medicine, Yale University, School of Medicine, New Haven, CT, (1985)
  • B.A., History, Yale College, New Haven, CT, (1980)

Academic Appointments

  • Professor of Neurology, George Washington University School of Medicine and Health Sciences
  • Professor of Pediatrics, George Washington University School of Medicine and Health Sciences
  • Professor of Neurology, Georgetown University
  • Professor of Hearing and Speech, University of Maryland, College Park

Biography

William D. Gaillard, M.D., is Chief of the Divisions of Child Neurology and of Epilepsy and Neurophysiology. He is Director of the Comprehensive Pediatric Epilepsy Program — one of the leading multidisciplinary pediatric epilepsy programs in the country. As Associate Director of the Children’s National Research Institute’s Center for Neuroscience Research, he is responsible for overseeing and organizing clinical neuroscience research. Dr. Gaillard is Professor of Pediatrics and Neurology at the George Washington University School of Medicine; Professor of Neurology, Georgetown University; and Adjunct Professor of Hearing and Speech Sciences, University of Maryland, College Park. Additionally, Dr. Gaillard holds longstanding collaborations with the Clinical Epilepsy Section (CES), National Institute of Neurological Disorders and Stroke and NIH.

His innovative research utilizes advanced structural and functional imaging to examine the effects of epilepsy on brain structure and function. His pioneering work with functional imaging has changed clinical practice for patients with epilepsy, made important technical contributions to structural and functional imaging methods, and provided fundamental scientific insights on the biology of brain plasticity. Ultimately, the goal of his research is to improve the outcomes and lives of children with epilepsy.

Dr. Gaillard is the President of the American Epilepsy Society  He is past Second Vice President and Treasurer of the American Epilepsy Society, past Chair of the International League Against Epilepsy (ILAE) Commission on Diagnostics, past Chair of the ILAE Pediatric Epilepsy Surgery Task Force and past member of the Pediatric Commission. He is an editor of Epilepsy Research and a past editor of Epilepsia. He is the author of more than 180 peer-reviewed scientific papers and more than 50 chapters and holds longstanding federal and foundation grant funding.

Research & Publications

Awards & Funding

NINDS RO1 (PI Edwin Trevathan MD MPH) 8/1/20-7/31/25  
Childhood Status Epilepticus and Epilepsy Determinants of Outcome (SEED) 
This study seeks to identify factors associated with recovery and mortality from children with status epilepticus in northern Nigeria. WD Gaillard consultant.  

NINDS R21NS109669 (PI WD Gaillard) 7/1/19-6/30/21
Novel Early Imaging Markers Following Febrile Status Epilepticus 
The aim of this study is to establish feasibility of establishing image biomarkers within 6 hours of febrile status epilepticus cessation to design anti-epileptogensis trials to prevent temporal lobe epilepsy and to identify mechanisms of neuronal injury through advanced imaging.  

NIDCD R01DC016902-01 (Co-PIs E Newport PhD, WD Gaillard MD) 12/1/18-1/30/23
Language and Cognition After Perinatal Stroke 
The  goal of this project is to examine the brain plasticity of language in children with a history of perinatal  left and right middle cerebral artery stroke using functional mapping with MRI to investigate the functional reorganization of language systems  informed by  cognitive/behavioral assessments.

U54 HD090257 (PI. V. Gallo, PhD) 8/1/06-11/31/26       
NIH, NICHD - IDDRC at Children’s National Medical Center
The main goal of this project is the operation of a center of excellence for research and training in the area of mental retardation and developmental disabilities in Washington, D.C. I direct the imaging core for this project.
WD Gaillard, MD: Associate Director IDDRC & Director Image Core 

BAND Foundation (PI. Z Grinspan MD) 1/1/21-12/31/22
Pediatric Epilepsy Mortality Initiative (PEMI)   
Brief Description: We will use the Pediatric Epilepsy Learning Healthcare System to identify and review deaths among children with epilepsy who have died from 2015 to 2021. WD Gaillard Co-Investigator

PERF (PI Z Grinspan MD) 9/1/17-8/30/21
A Learning Healthcare System for Pediatric Epilepsy
This proposal will builds a foundation for ongoing epilepsy research by creating computable phenotypes for subtypes of pediatric epilepsy and  creating common data elements for data collection at the point of care across 20 pediatric epilepsy centers. WD Gaillard Co-Investigator

Hess Foundation (PI WD Gaillard) 5/1/19-4/30/22
This fund supports behavioral health support and studies in child ren with epilepsy and advanced imaging in children with focal epilepsy