Nobuyuki Ishibashi, M.D.

Nobuyuki Ishibashi, M.D., is Director of the Cardiac Surgery Research Laboratory and Foglia-Hills Professor of Pediatric Cardiac Research at Children’s National Hospital. He holds an appointment as Associate Professor of Pediatrics and Pharmacology and Physiology at George Washington University. Previously Dr. Ishibashi completed clinical training in Surgery, Cardiovascular Surgery, and Pediatric Cardiac Surgery at the Heart Institute of Japan, Tokyo Women’s Medical University. His research activities focus on studying how congenital heart disease (CHD) and subsequent cardiac surgery affect the rapidly developing brain. The Ishibashi laboratory has successfully utilized sophisticated and cutting-edge neuroscience techniques to study brain development in clinically-relevant animal models of CHD. Dr. Ishibashi has recently demonstrated the relationship between the subventricular zone and cortical growth in CHD. As a clinician scientist the long-term goal of his research program is to optimize treatment strategy and develop new approaches that will reduce neurodevelopmental impairment in children with CHD. Results from his translational program have lead to development of a Phase 1 clinical trial (MeDCaP trial, NCT04236479) at Children’s National, of which he is co-principal investigator.

Research and Publications