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The Children's Research Institute

Research Profile

Education & Training

  • M.D., Medicine, Mount Sinai School of Medicine, New York, NY, (1968-1972)
  • Residency, Pediatrics, Children's Hospital, Washington, DC, (1972-1974)
  • Fellowship, Pediatric Hematology/Oncology, New York Hospital Cornell Medical Center, New York, NY, (1974-1976)
  • Special Fellowship, Transfusion Medicine, Memorial Sloan Kettering New York Blood Center, New York, NY, (1976)

Academic Appointments

  • Professor of Pediatrics and Pathology, George Washington University School of Medicine and Health Science

Biography

My research interests are focused on clinical and translational investigations of transfusion safety and include studies of infectious and non-infectious complications of transfusion, including RBC and HLA alloimmunization, graft versus host disease, and evidence based transfusion practices. Recent studies include the molecular characterization of genes associated with alloimmunization and genetic modifiers of hemoglobin F expression.

I have served NHLBI, FDA, and AABB in a number of roles including Special Emphasis Panels and review groups as the transfusion consultant for STOP I, II, SWiTCH and TWiTCH. I served on NHLBI Council from 2011-2014. As Vice Chair of Academic Affairs, I have established, directed, or co-directed training programs for junior and women faculty including K30, Pediatric Clinical Research, and Sickle Cell Scholar Programs and a T32. I am the program director of our KL2 and oversee other K awardees' career development awards. I am responsible for academic and research education programming, including the development of resident, fellow, junior, and master mentorship programs, grants training seminars, and career development initiatives. I review for the NHLBI’s Loan Repayment Program and serve on several K12 External Advisory Committees. I have mentored over 30 fellows and junior faculty, most of whom are now in academic positions in pediatric hematology.

This faculty member (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.

Outside Interests

  • Corman University of Iowa 
  • American Society of Pediatric 
  • Hematology 
  • Oncology 
  • Immucor  

Research & Publications