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The Children's National Research Institute

Research Profile

Research Interests

  • Pediatric solid tumors

  • Renal tumors

  • Wilms' tumor

  • Osteosarcoma

  • Rhabdoid tumor

  • Renal cell carcinoma

Academic Appointments

  • Professor of Pediatrics, George Washington University of Medicine and Health Sciences


Jeffrey Dome, M.D., Ph.D., is Vice President of the Center for Cancer and Blood Disorders, Chief of the Division of Oncology, and Associate Director of the Center for Cancer and Immunology Research at Children’s National Hospital in Washington, D.C. He also is Professor of Pediatrics at the George Washington University School of Medicine & Health Sciences and the Thomas Willson and Lenore Williams McKnew Professor of Pediatric Oncology. Dr. Dome received his M.D. degree from the University of Pennsylvania School of Medicine and his Ph.D. degree in Medicine from Erasmus University in Rotterdam. He completed a residency in Pediatrics at Yale-New Haven Hospital and a fellowship in Pediatric Hematology/Oncology at Johns Hopkins Hospital.

After fellowship, Dr. Dome was a faculty member at St. Jude Children’s Research Hospital before joining Children’s National Hospital in 2006. Dr. Dome is an internationally recognized expert on pediatric solid tumors, with an emphasis on kidney tumors and sarcomas. He chaired the Children’s Oncology Group (COG) Renal Tumor Committee, which oversees clinical research on kidney tumors at more than 200 children’s hospitals around the world, for more than 10 years. Dr. Dome is the Continental President of North America for the International Society of Paediatric Oncology (SIOP). He is a member of the Hematology/Oncology Subboard of the American Board of Pediatrics and serves on numerous medical advisory boards for cancer foundations. He has authored more than 150 articles, books and chapters on pediatric cancer.

This faculty member (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.

Outside Interests

  • American Board of Pediatrics 
  • St Jude Children's Research Hospital 
  • Sigma-Tau Pharmaceuticals,, Inc. 

Research & Publications