Research

Discoveries for Today’s Therapies, Tomorrow’s Cures

Children’s National takes on some of the most daunting medical research issues to improve children’s lives.

Our research efforts are two-fold: to cure many of childhood's most serious and deadly diseases, and to develop innovative therapies and treatments to improve children’s quality of life. 
Overview

Overview

The physicians, scientists, and nurses at Children’s National work together to conduct translational, clinical, and community research. The work includes genome-enabled research, pre-clinical studies of experimental therapeutics, and clinical trials in such areas as childhood cancer, genetic and rare disorders, developmental disabilities, and behavioral disorders.

At any given time, Children’s National has at least 100 clinical trials open. By partnering with hospitals and universities around the world, we are accelerating progress for children globally.
Cancer and Immunology

Cancer and Immunology

Our research into cancer and related immunological issues includes investigating oncological causes, responses to tumors, and treatment. Of particular focus have been studies of hematologic disorders, including sickle cell disease, bone marrow and stem cell transplantation, and infectious diseases that affect children.

Genetics

Genetics

Genome-enabled research, pre-clinical studies of experimental therapeutics, and clinical trials carry great potential for improving children’s lives. New discoveries in genetics make it possible to predict and intervene to minimize risks from childhood through adulthood.

Neuroscience

Neuroscience

Our researchers seek a better understanding of how the central nervous system develops, as well as the cellular and molecular mechanisms of brain dysfunction. Research is focused on eight major areas: autism; brain development; developmental disabilities; fetal and neonatal brain injury; neural stem cells and developmental neurobiology; neurofibromatosis; neuro-oncology; and pediatric epilepsy.

Surgery

Surgery

The Sheikh Zayed Institute for Pediatric Surgical Innovation at Children’s National is redefining surgery for children. By combining research and clinical expertise, the Institute’s team members are working to make making surgery more precise, less invasive, and pain-free. Researchers collaborate with our surgical team and partners throughout the world, thanks to a major philanthropic gift from the Government of  Abu Dhabi.

Translational Science

Translational Science

Our translational science focuses on applying basic research to innovative treatment of childhood diseases, particularly among disadvantaged youth, to address healthcare disparities. We focus on some of the nation’s most serious pediatric conditions, such as HIV/AIDS, asthma, obesity, and sudden infant death syndrome. Through translational research, we move scientific discoveries into therapeutic and preventive applications that help children survive and thrive.

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