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Participants Needed for Asthma Prevention Study

baby grabbing doctor's stethoscope

The ORBEX Study is a three year study conducted at Children's National to learn more about preventing wheezing and asthma in young children. The purpose of the study aims to see if a medication can help prevent wheezing in infants who are at risk for developing asthma.

We are inviting children under the age of 17 months who meet one or more of the following requirements to participate:

  • The child has eczema
  • One of the child’s parents has or had asthma
  • The child has a sibling aged four years or older with asthma

Study Details:

After the first visit, there will be a trial period to see how well you follow a practice medication schedule for your child. If you are able to give your child the capsules most of the time, your child will be randomly assigned to take either the study medication or a placebo capsule. You will not know which one your child is taking.

  • The study will last three years.
  • There will be 12 planned study visits and 26 planned study phone calls throughout the three years. Participants will be reimbursed for each completed study visit and monthly phone call.
  • You will give your child the study capsules for 10 days every month for the first two years of the study.
  • Testing includes a physical examination and collection of blood, stool and nasal samples.

For more information, please contact Trisha Ibeh at 202-476-2628.