Roger Packer, MD Senior Vice President | Center for Neuroscience & Behavioral Health

Awards and Recognition:

    Top Doctors
    (2015, 2016)
    No. Va. Magazine
    (2016, 2017)

View My Research Profile


Languages Spoken

  • English


Board Certifications

  • American Board of Pediatrics
  • American Board of Psychiatry/Neurology-Child Neuro

National Provider ID: 1821175167

This faculty member (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.

Outside Interests

  • DSMB Roche Pharmaceutical



Roger J. Packer, MD, is Senior Vice-President, Center for Neuroscience and Behavioral Medicine, Gilbert Distinguished Professor of Neurofibromatosis, and is Director of both the Gilbert Neurofibromatosis Institute and the Brain Tumor Institute of Children’s National Health System. Dr. Packer’s present academic titles include Professor of Neurology and Pediatrics at George Washington University and Clinical Professor of Neurosurgery at the University of Virginia in Charlottesville, Virginia. He holds the Gilbert Family Distinguished Professorship in Neurofibromatosis. Prior to coming to Children’s National, Dr. Packer was Director of the Brain Tumor Program and Professor of Neurology and Pediatrics at the Children’s Hospital of Philadelphia, University of Pennsylvania.

Throughout his career, Dr. Packer has been heavily involved in clinical and applied basic science research. His clinical research has touched on various aspects of adult and child neurology and neuro-oncology, including adult and pediatric brain tumors, neurofibromatosis type 1, the neurologic aspects of childhood neurogenetic diseases, and multiple other topics in general child neurology. Much of his research has focused on the development and performance of clinical trials for adults and children with neurologic, neuro-oncologic, and neurogenetic disorders, and he has received peer-reviewed grant support for this research. Many of the clinical trials in Neurofibromatosis and brain tumors are translational, bringing advances from the bench to the bedside expeditiously.

Presently, Dr. Packer is principal investigator at Children’s National for the Pediatric Brain Tumor Consortium (PBTC), formed under the auspices of the National Cancer Institute; Chairman of the PBTC Low-Grade Glioma Committee; Group Chair of the Neurofibromatosis Clinical Trials Consortium; is Chair of the Medulloblastoma Committee of the Children’s Oncology Group; P.I. for the Institution as part of the NINDS-sponsored Neuro-NEXT Clinical Trials Consortium; and P.I. of its NSADA award.  He has worked closely with the NCI and NINDS, and has served on multiple committees setting the directions for neurologic clinical and basic science research for the future. He headed the efforts in pediatrics for the program review, held by the NCI and NINDS, for brain tumors. Much of Dr. Packer’s clinical research has been translational in nature. He has been part of studies evaluating the molecular genetics of childhood and adult neurologic diseases and also has coordinated the first gene therapy study for children with malignant brain tumors in the U.S. The majority of the studies now being coordinated by Dr. Packer are studies evaluating innovative agents aimed at the molecular underpinnings of neurologic disease. He has published over 325 original articles and 300 reviews and chapters.

Education & Training

Education & Training

  • Fellowship Program, Pediatric Neurology, 1981
    Children's Hospital of Philadelphia
  • Fellowship Program, Neurology, 1981
    Children's Hospital of Philadelphia
  • Fellowship Program, Pediatric Neuro-Oncology, 1981
    Memorial Sloan-Kettering Cancer Center
  • Residency Program, Pediatrics, 1978
    Cincinnati Children's Hospital Medical Center
  • MD, 1976
    Northwestern University Feinberg School of Medicine
  • BS, 1972
    Northwestern University
Patient Stories

Patient Stories: Roger Packer

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Lexy's Story

Sixteen-year-old West Virginia native Lexy Blair and her parents knew that something was wrong when she started needing to take breaks during her favorite dance classes.

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Ida's Story

Ida Namazi is a bright, ambitious 21-year-old University of Virginia junior who dreams of attending law school and becoming a senator one day. What people might not know about Ida is that she was diagnosed with neurofibromatosis type 1 (NF1) when she was a toddler and has been battling the neurologic condition her whole life.



Children's National Health System Hosts First International Pediatric Low-Grade Glioma Symposium

Under the direction of Roger Packer, MD, 35 clinical and translational researchers from across the United States, Canada, and Europe, gathered in Washington, DC, to share cutting-edge research results and create the backbone of future studies, which hold the hope of dramatically changing the ways childhood low-grade gliomas are treated in the future. The conference was co-sponsored by Children’s National and the Pediatric Low-Grade Glioma Association.

Research & Publications

Research & Publications

Biologic background of pediatric medulloblastoma and ependymoma A review from a translational research standpoint

(2008) Neuro-Oncology

Central nervous system germ cell tumors of childhood presentation and delay in diagnosis

(2007) Neurology

Long term outcome among adult survivors of childhood central nervous system malignancies A report from the Childhood Cancer Survivor Study

(2009) Journal of the National Cancer Institute

Long term outcome among adult survivors of childhood central nervous system malignancies A report from the Childhood Cancer Survivor Study

(2009) Journal of the National Cancer Institute

Massachusetts General Hospital Neurology Grand Rounds

(2011) Improved Outcome for Children with Medulloblastoma in the Molecular Era

Medulloblastoma in childhood new biologic advances

(2007) Lancet Neurology

Minneapolis Childrens Hospital Pediatric Grand Rounds

(2011) Molecular Insights of Medulloblastoma: Towards More Effective Therapy

Objective response of multiply recurrent low grade gliomas to bevicizumab and irinotecan

(2009) Pediatric Blood and Cancer

Phase I study of concurrent RMP7 and carbopatin with radiation therapy for children with newly diagnosed brainstem gliomas

(2005) Cancer

Phase I trial of pirfenidone in children with neurofibromatosis type 1 and plexiform neurofibromas

(2007) Journal of Pediatric Neurology

Phase III prospective randomized study of craniospinal radiation therapy followed by one of two adjuvant chemotherapy regimens for newly diagnosed average risk medulloblastoma

(2006) Journal of Clinical Oncology

View publications on PubMed

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