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Michele L. Mietus Snyder, MD

The Diana L. and Stephen A. Goldberg Center for Community Pediatric Health

Co-Director, Obesity Institute

Preventive Cardiology Program

Children’s Research Institute (CRI)
Center for Translational Science
Specialties: Cardiometabolic Syndrome, Pediatric Weight Management

Board CertificationsAmerican Board of Pediatrics
National Provider Identifier1619077237

Service LocationsChildren's National Medical Center - Sheikh Zayed Campus for Advanced Children's Medicine
111 Michigan Avenue, NW
Washington, DC 20010
Map | Driving Directions
Phone: 202-476-5000

Children's Outpatient Center in Spring Valley

4900 Massachusetts Avenue, NW
Suite 320
Washington, DC 20016
Map | Driving Directions

Phone: 202-895-3860
Fax: 202-895-3870

Dr. Mietus-Snyder is a preventive cardiologist and clinical research scientist transitioning in 2010 from The University of California, San Franciso to a position as Co-Director of the Children’s National Obesity Institute. Her early basic science research on genes important in early atherosclerosis impressed upon her how many cardiovascular risk factors function via common metabolic pathways that promote vascular oxidative stress, including unhealthful diet, sedentary lifestyle, dyslipidemia, hypertension, and psychosocial stress. The growing epidemic of childhood obesity places children, especially minority children, at heightened risk for early atherosclerotic disease through all of these pathways.

Dr. Mietus-Snyder’s current research is focused on the identification of lifestyle strategies to improve metabolic balance and heart health for all children, independent of economic circumstances. She is the Principal Investigator of a project entitled “Stress, Inflammation, and the Metabolic Syndrome” funded by the American Heart Association evaluating the role of psychosocial stress on the disproportionate burden of obesity and its cardiometabolic complications in inner city children. She is also coinvestigator on a longstanding research collaboration with Dr. Bruce Ames at The Children’s Hospital Oakland Research Institute and the USDA Nutritional Research Laboratory in Albany, CA exploring the nutritional underpinnings of energy dysregulation and metabolic dysfunction.
TypeSchoolLocationDegreeField of StudyYears
Undergraduate Education University of California- San Diego School of Medicine La Jolla, CABachelor of Arts 1973 -1978
Medical School University of California- San Diego School of Medicine La Jolla, CADoctor of Medicine 1978 -1982
National & International Recognitions
Clinical Science AchievementAchievement Rewards for College Scientists Foundation1994
A. Baird HastingsMedical Honor Society1982
Phi Beta KappaAcademic Honor Society1978

Affiliations and Memberships
TitleInstitutionCommittee / SectionYears
National Association of Children’s Hospitals and Related InstitutionsFocus Group for a Fitter Future2010 - 2012
American Heart AssociationCouncil for Cardiovascular Disease in the Young2000
National Lipid AssociationNew England Preventive Cardiology Subgroup2008
American Academy of PediatricsProvisional Section on Obesity2010
TitleStudy NameInstitutionYears
InvestigatorAttenuating the Micronutrient Malnutrition of OvernutritionAmes Foundation2005 - 2011
Principal InvestigatorExpanding Lifestyle Counseling in Overweight Minority Children to Include Stress Reduction; Impact on the Metabolic SyndromeAmerican Heart Association2006 - 2010
Journal Article, Frassetto, LA, Schloetter, M, Mietus-Snyder, M, Morris, RC Jr, and Sebastian, A. (2010), Metabolic and physiologic improvements from consuming a Paleolithic-hunter-gatherer-type diet., Eur J Nutrition., 63, 947-955.

Other, Lim JS, Mietus-Snyder, M, Valente, A, Schwarz JM, Lustig, RH. (2010), Nature Reviews Gastroenterology and Hepatology., The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome..

Other, Urbina, E, Williams, , Alpert, B, Daniels, SR, Hayman, L, Jacobson, M, Mahoney, L, Mietus-Snyder, M, Rocchini, A, Steinberger, J, and McCrindle, B. (2009), Hypertension, Non-invasive Vascular Assessment of Subclinical Vascular Disease in Children and Adolescents: Recommendations for Standard Assessment., 54, 5, 919-950.

Other, Steinberger, J, Daniels, SR, Eckel, RH, Hayman L, Lustig, McCrindle, B, Mietus-Snyder, M. (2009), Circulation. , Progress and Challenges in Metabolic Syndrome in Children and Adolescents., 119, 628-647.

Journal Article, Madsen KA, Garber A, Mietus-Snyder M, Orrell-Valente J, Tran CT, Wlasiuk L, Matos RI, Neuhaus J, Lustig R. (2009), A clinic-based lifestyle intervention for pediatric obesity: efficacy and behavioral and biochemical predictors of response., J Pediatr Endocrinol Metab., 22, 805-814.

Other, Urbina, E, Alpert, B, Flynn, J, Hayman, L, Harshfirld, G, Jacobson, M, Mahoney, L, McCrindle, B, Mietus-Snyder, M, Steinberger, J, Daneils, S. (2008), Hypertension. , Ambulatory Blood Pressure Monitoring in Children and Adolescents: Recommendations for Standard Assessment., 52, 433-451.

Journal Article, Lustig,R, Mietus-Snyder, M, Bacchetti, P, Lazar, A, Velasquez-Mieyer, PA, Christensen, ML. (2006), Insulin dynamics predict response to insulin suppression or sensitization pharmacotherapy in obese children. , J Pediatr., 148, 23-29.

Journal Article, Engler, MM, Engler, MB, Malloy, MJ, Paul, SM, Kulkarni, KR, Mietus-Snyder, M. (2005), Effect of docosahexaenoic acid on lipoprotein subclasses in hyperlipidemic children (the EARLY study)., Am J Cardiol., 95, 869-871.

Journal Article, Soep, J., Mietus-Snyder, M., Malloy, M., Witztum, J.L., and von Scheven, E. (2004), Assessment of atherosclerotic risk factors and endothelial function in children and adolescents with systemic lupus erythematosus., Arthritis Rheum., 51, 451-457.

Journal Article, Mietus-Snyder, M. and Pitas, R.E. (2000), Class A Scavenger Receptor Upregulation in Smooth Muscle Cells by Oxidized LDL: Enhancement by Calcium Flux and Coincident Cyclooxygenase-2 Upregulation., J. Biol. Chem..

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