Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA) Resources


The EMSC National Resource Center has produced a series of promotional materials on the Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA) trials developed with the support of the THAPCA resource team at the University of Utah and the National Heart, Lung, and Blood Institute (NHLBI). All materials are intended to raise awareness among providers and families about the THAPCA trials.

While therapeutic hypothermia has been studied in adults after cardiac arrest and newborn infants diagnosed with perinatal asphyxia, there has not been a controlled trial evaluating the efficacy of hypothermia in pediatric cardiac arrest in either the inpatient or out-of-hospital setting. The THAPCA study is evaluating whether regulating the body temperature improves survival with good neurobehavioral outcomes in children after cardiac arrest. Separate study arms are being conducted for children who arrest in the hospital and children who arrest out of the hospital. Enrollment began in September 2009 and will continue through 2014. Currently the study is in 35 clinical sites across the United States. Please contact Jaclynn Haymon at the EMSC National Resource Center if you have any feedback or questions about these resources. For more information about THAPCA, visit  the THAPCA website.

  • Clinician Education Module. This education module targets in-hospital clinicians, such as Pediatric Intensive Care Unit (PICU) nurses, who may be more likely to encounter children with cardiac arrest. The module highlights important information about pediatric cardiac arrest, the purpose of the THAPCA study, and the role of the clinician.

  • Fact Sheet for Prehospital Providers. This fact sheet is intended for prehospital providers who may encounter children suffering from out-of-hospital cardiac arrest. The purpose of the fact sheet is to keep providers informed of the study.

  • Getting Started: A Guide for Parents and Guardians. This brochure targets the parent or guardian of a child suffering from cardiac arrest. The brochure can be used prior to or during the enrollment process with THAPCA and provides the reader with important information about the study, including the risks and potential benefits of participation.

  • Study Poster for Clinicians. This poster is intended for clinicians in the emergency department and PICU to make them aware of the THAPCA trials and how to get involved.

  • Study Poster for Families. This poster is intended for families in the emergency department and PICU to make them aware of the THAPCA trials and where to go for more information.

This study, funded by the NHLBI, is a joint effort between the Pediatric Emergency Care Applied Research Network (PECARN) funded through the EMSC Program and the National Institutes of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.