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Pediatric Clinical Trials

At Children’s National, we never stop. We never stop researching new treatments methods for cancer, or improving existing therapies. As the fight against cancer evolves, we are on the front lines, participating in and leading research trials to offer new hope for cancer patients.

Children’s Research Institute: Fighting Childhood Cancer 

Children’s National Health System is a leader in medical research and education programs. Our clinical and research teams work to improve prevention, treatment and care of childhood diseases. 

Clinical trials have two main goals:

  • Bringing new, more effective therapies to your child’s care while minimizing side effects
  • Arriving at a better, more precise understanding of childhood disease and advancing the field of targeted therapies 

Our scientists conduct research to gain a deeper understanding of childhood diseases. This means that we continuously bring our findings to your child’s bedside, providing the most advanced care for children. Learn more about the Children’s Research Institute (CRI).

Clinical Trials at Children’s National 

We do more than offer the most advanced techniques and treatments available today. We are also working tirelessly to investigate the newest drugs and therapies, which will minimize side effects and improve quality of life for our patients. 

Our team members established clinical trials in treating brain and renal tumors, and they are leaders in research on pediatric solid tumors. We are also the only hospital in the Washington, DC, region, and one of only a handful in the country with access to:

  • Children’s Oncology Group Phase I Trials
  • Pediatric Brain Tumor Consortium protocols 

What is a Phase I Clinical Trial?

Clinical trials evaluate the biology and safety of new medications or medical devices. Phase I Clinical Trials are the most basic type of study, and investigators test drugs to evaluate the way the body reacts to them at different doses to ensure their safety.  

Researchers on Phase I trials subject all studies to rigorous quality control and monitoring to ensure the identification of safe, effective doses. Then, we can incorporate them into wider-scale pediatric clinical trials. 

To learn more about current studies, we invite you to search the database of clinical trials offered through Children’s Research Institute at Children’s National. You can also speak with a member of your child’s care team at any time.  

Contact Us

For more information, call us at 1-202-476-2800.

Children's Team

Children's Team


Jeffrey Dome

Jeffrey Dome

Vice President, Center for Cancer and Blood Disorders


Leukemia Lymphoma Program

We deliver comprehensive care for all blood cancers including chemotherapy, bone marrow transplant and experimental therapeutics.


Our oncology (cancer) team provides personalized treatment plans for children with cancer, including access to clinical trials.

Solid Tumor Program

Our Solid Tumor Program has a dedicated team of sarcoma experts who specialize in the newest treatments and clinical trials.

Comprehensive Sickle Cell Disease Program
The Comprehensive Sickle Cell Disease Program at Children’s National is among the largest pediatric sickle cell disease programs in the country.

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