Adre Du Plessis, MBChB Director, Fetal Medicine Institute



Adré J du Plessis, MBChB, is a full time attending in fetal neurology, as well as the Director of the Fetal Medicine Institute, Division Chief of Fetal and Transitional Medicine, and Director of the Fetal Brain Program at Children's National Health System. In addition, Dr. du Plessis is a Professor of Pediatrics and Neurology at George Washington University School of Medicine.

Dr. du Plessis is a leading international expert in the normal and abnormal development of the brain, as well as the mechanisms of injury to the immature brain. Under his leadership, the Fetal Medicine Institute provides individualized and specialized care to patients during and after the baby’s birth.

Dr. du Plessis received his MBChB from the University of Cape Town, South Africa. He trained in pediatrics at the University of Cape Town, South Africa and Penn State University, PA. In addition, he trained in child neurology at the St. Louis and Boston Children’s Hospitals.

Prior to joining the staff at Children's National, Dr. du Plessis spent two decades at Boston Children's Hospital and Harvard Medical School; where he was an Associate Professor of Neurology. While in Boston, he developed and directed the Critical Care Neurology and Fetal-Neonatal Neurology programs in the Department of Neurology at Boston Children's Hospital. These were the first such programs of their kind anywhere, and they continue to be the largest. These programs served as a model for the Fetal Medicine Institute at Children's National.

Dr. du Plessis specializes in fetal neurology, particularly fetal brain developmental anomalies and the advanced fetal imaging that is used to diagnose these conditions in early pregnancy. His career-long research focus has been on the nervous system of the fetus and newborn, the hazards and mechanisms of injury, and the potential prevention of insult to the brain.

Education & Training

Education & Training

  • MPH, 1995
    Harvard School of Public Health
  • Fellowship Program, Pediatric Neurology, 1993
    Children's Hospital of Boston
  • Residency Program, Pediatric Neurology, 1991
    Children's Hospital of Boston
  • Residency Program, Child Neurology, 1990
    St. Louis Children's Hospital
  • Residency Program, Neurology, 1989
    Barnes Jewish Hospital
  • Residency Program, Pediatrics, 1988
    Pennsylvania State University College of Medicine
  • Internship Program, Pediatrics, 1987
    Pennsylvania State University College of Medicine
  • MBCHB, 1980
    University of Cape Town
Patient Stories

Patient Stories: Adre Du Plessis

Teresa's Story

"The thing I like most about Children's National is that they don't just take great care of the sick children, but they also take great care of the whole family."

Patient story

Austin's Story

"People always tell me 'You're so strong, I don't know how you got through it.' I like to say that you never know how strong you are or what you are capable of until you have no choice but to be strong." 



Prenatal Care

Children's National Experts Discuss Importance of Fetal Cardiology Subspecialty to Fetal Medicine

Earlier this year, the American Heart Association (AHA) released a scientific statement on the diagnosis and treatment of fetal cardiac disease written by a team of cardiac and obstetrical experts with lead author, Mary T. Donofrio, MD, Director of the Fetal Heart Program and Medical Director of the Critical Care Delivery Program for the Fetal Medicine Institute at Children’s National Health System.

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