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David Leitenberg, MD, PhD - Center for Cancer and Immunology Research - Children's Research Institute - Children's National Medical Center David Leitenberg, MD, PhD

David Leitenberg Children's National Medical Center
Faculty, Children's Research Institute (CRI), Center for Cancer and Immunology Research (CCIR)

George Washington University
School of Medicine and Health Sciences
Associate Professor, Microbiology, Immunology and Tropical Medicine; Pediatrics; Pathology

Contact Information
Children's National Medical Center
Center for Cancer and Immunology Research (CCIR)
111 Michigan Avenue, NW
Washington, DC 20010-2970

202-476-5000


Education & Training
Institution & Location Degree Year(s) Field of Study
University of Vermont, Burlington, VT
BA
1983 Zoology
University of Iowa, Iowa City, IA
MD
1990 Medicine
University of Iowa, Iowa City, IA PhD
1990
Immunology
Yale-New Haven Hospital, New Haven, CT Resident
1990 -
1993
Clinical Pathology
Yale University, New Haven, CT
Fellow
1993 -
1995
Immunobiology

Research Interests
Dr. Leitenberg serves as Director of the Immunology Laboratory in the Division of Laboratory Medicine at Children’s National Medical Center. His expertise is in the flow cytometric diagnosis of immunodeficiency syndromes and hematologic neoplasms.

Dr. Leitenberg's research is focuses on the regulation of cell fate decisions in T lymphocytes.  Understanding the factors that regulate lymphocyte survival and development into functionally distinct subsets is critical for the rational design of therapeutic strategies to enhance protective immune responses to infectious diseases and tumors, as well as to ameliorate harmful immune responses in autoimmune and inflammatory disorders.

Projects in Leitenberg's laboratory are broadly based on the hypothesis that signal transduction events that regulate cell fate decisions are developmentally regulated and modulated by the tissue microenvironment. His current projects involve the roles of the CD45 protein tyrosine phosphatase and the CD4-associated src family tyrosine kinase, Lck, in selectively regulating cell development and survival and in regulating host-immune response in vivo.


Clinical Interests 
Click here for more information about this doctor's clinical practice, including how to make an appointment.

Publications
View a partial list of publications for David Leitenberg through the National Library of Medicine's PubMed online database.


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