PECARN

The Health Resources and Services Administration, Maternal and Child Health Bureau, EMSC Program continues its efforts in high-priority research by investing $14.4 million over the next four years (2016-2019) in to the Pediatric Emergency Care Applied Research Network (PECARN). Founded in 2001, PECARN is the first and only federally-funded pediatric emergency medicine research network in the United States.

PECARN consists of six research node centers, each of which is comprised of three hospital emergency department (ED) affiliates and one prehospital Emergency Medical Services (EMS) agency affiliate. In addition, PECARN includes a prehospital EMS research node with three EMS affiliate sites funded through the EMSC Targeted Issues grant program.

Together, these entities conduct multi-institutional research on the prevention and management of acute illnesses and injuries in children and youth of all ages. The 18 EDs (representing academic, community, urban, general, and children’s hospitals) and the nine EMS agencies serve approximately 1.1 million pediatric patients and conduct more than 68,000 pediatric EMS runs annually. Since its inception, PECARN has published 88 peer-reviewed manuscripts.

The PECARN research nodes include:

  • Great Lakes Emergency Medical Services for Children Research Network (GLEMSCRN) led by Principal Investigator Rachel Stanley, MD, MHSA, located at Nationwide Children’s Hospital. GLEMSCRN conducts its research in collaboration with the following pediatric EDs and EMS affiliate:
    • Nationwide Children’s Hospital, Columbus, OH
    • Children's Hospital of Michigan, Detroit, MI
    • University of Michigan, Ann Arbor, MI
    • Columbus Division of Fire, Columbus, OH
  • Hospitals of the Midwest Emergency Research Node (HOMERUN) led by Principal Investigator Richard Ruddy, MD, located at Cincinnati Children’s Hospital Medical Center. HOMERUN conducts its research in collaboration with the following pediatric EDs and EMS affiliate:
    • Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
    • Washington University & St. Louis Children’s Hospital, St. Louis, MO
    • Children’s Hospital of Wisconsin & Medical College of Wisconsin, Milwaukee, WI
    • City of Cincinnati Fire Department, Cincinnati, OH
  • Pediatric Emergency Medicine Northeast, West and South (PEM-NEWS) led by Principal Investigator Peter Dayan, MD, MSc, located at Children’s Hospital of New York. PEM-NEWS conducts its research in collaboration with the following pediatric EDs and EMS affiliate:
    • Children’s Hospital of New York, New York, NY
    • Texas Children’s Hospital, Houston, TX
    • The Children’s Hospital of Colorado, Aurora, CO
    • Aurora Fire Department, Aurora, OH
  • Pediatric Research in Injuries and Medical Emergencies (PRIME) led by Principal Investigator Nathan Kuppermann, MD, MPH, located at University of California, Davis. PRIME conducts its research in collaboration with the following pediatric EDs and EMS affiliate:
    • Children’s Hospital of Philadelphia, Philadelphia, PA
    • University of Utah & Primary Children’s Medical Center, Salt Lake City, UT
    • University of California, Sacramento, CA
    • Sacramento Fire Department, Sacramento, CA
  • Washington, Boston, Chicago Applied Research Node (WBCARN) led by Principal Investigator James Chamberlain, MD, located at Children’s National Health System. WBCARN conducts its research in collaboration with the following pediatric EDs and EMS affiliate:
    • Children’s National Health System, Washington, DC
    • Children’s Hospital Boston, Boston, MA
    • Chicago Memorial Northwestern, Chicago, IL
    • Prince George's County Fire/EMS Department, Upper Marlboro, MD
  • Southwest Research Node Center (SW-RNC) led by Principal Investigator Kurt Denninghoff, MD, located at the University of Arizona Health Sciences Center. The node includes the following pediatric EDs and EMS affiliate:
    • University of Arizona Health Sciences Center, Tucson, AZ
    • University of New Mexico Health Sciences Center, Albuquerque, NM
    • Oklahoma University Health Sciences Center, Oklahoma City, OK
    • New Mexico EMS Consortium
  • Charlotte, Houston, Milwaukee Prehospital EMS Research Node (CHaMP) led by Principal Investigator Brooke Lerner, PhD, located at the Medical College of Wisconsin. The node includes the following EMS Affiliates:
    • Milwaukee County EMS, Milwaukee, WI
    • Mecklenburg EMS Agency (Medic), Charlotte, NC
    • Houston Fire Department EMS, Houston, TX.

Current PECARN studies enrolling patients include:

  1. Fluid Therapy and Cerebral Injury in Pediatric Diabetic Ketoacidosis;
  2. Emergency Department Screen for Teens at Risk for Suicide (ED-STARS).
  3. Probiotics - Impact of Emergency Department Probiotic Treatment of Pediatric Gastroenteritis.

Soon, PECARN will also begin enrollment for the Established Status Epilepticus Treatment Trial (ESETT).

For more information about these and other current and recently completed PECARN studies, visit the PECARN web site. To submit a study idea to PECARN, visit the site’s training module.