Michele Mietus Snyder, MD Cardiologist



Michele Mietus-Snyder, MD, is a preventive cardiologist and clinical research scientist transitioning in 2010 from The University of California, San Francisco, to a position as Co-Director of the Children’s National Obesity Institute.Her early basic science research on genes important in early atherosclerosis impressed upon her how many cardiovascular risk factors function via common metabolic pathways that promote vascular oxidative stress, including unhealthful diet, sedentary lifestyle, dyslipidemia, hypertension, and psychosocial stress. The growing epidemic of childhood obesity places children, especially minority children, at heightened risk for early atherosclerotic disease through all of these pathways.

Dr. Mietus-Snyder’s current research is focused on the identification of lifestyle strategies to improve metabolic balance and heart health for all children, independent of economic circumstances. She is the Principal Investigator of a project entitled “Stress, Inflammation, and the Metabolic Syndrome” funded by the American Heart Association evaluating the role of psychosocial stress on the disproportionate burden of obesity and its cardiometabolic complications in inner-city children. She is also co-investigator on a longstanding research collaboration with Dr. Bruce Ames at The Children’s Hospital Oakland Research Institute and the USDA Nutritional Research Laboratory in Albany, CA, exploring the nutritional underpinnings of energy dysregulation and metabolic dysfunction.

Education & Training

Education & Training

  • Fellowship Program, Pediatric Cardiology, 1988
    Children's Hospital Boston - Harvard
  • Residency Program, Pediatrics, 1985
    Children's Hospital Boston - Harvard
  • Internship Program, Pediatrics, 1983
    Children's Hospital Boston - Harvard
  • MD, 1982
    University of California- San Diego School of Medicine
  • BA, 1978
    University of California- San Diego School of Medicine
Patient Stories

Patient Stories: Michele Mietus Snyder

Patient story

Alexis's Story

"She likes to show off her scar and tell whoever listens that Children's National fixed her heart."



Research & Publications

Research & Publications

A clinicbased lifestyle intervention for pediatric obesity efficacy and behavioral and biochemical predictors of response

(2009) J Pediatr Endocrinol Metab.

Ambulatory Blood Pressure Monitoring in Children and Adolescents Recommendations for Standard Assessment

(2008) Hypertension.

Assessment of atherosclerotic risk factors and endothelial function in children and adolescents with systemic lupus erythematosus

(2004) Arthritis Rheum.

Class A Scavenger Receptor Upregulation in Smooth Muscle Cells by Oxidized LDL Enhancement by Calcium Flux and Coincident Cyclooxygenase2 Upregulation

(2000) J. Biol. Chem.

Effect of docosahexaenoic acid on lipoprotein subclasses in hyperlipidemic children the EARLY study

(2005) Am J Cardiol.

Metabolic and physiologic improvements from consuming a Paleolithichuntergatherertype diet

(2010) Eur J Nutrition.

Noninvasive Vascular Assessment of Subclinical Vascular Disease in Children and Adolescents Recommendations for Standard Assessment

(2009) Hypertension

Progress and Challenges in Metabolic Syndrome in Children and Adolescents

(2009) Circulation.

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome

(2010) Nature Reviews Gastroenterology and Hepatology.

View publications on PubMed

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Labor Day 2012

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