Mary T. Donofrio, MD, is a Professor of Pediatrics and full-time attending in the Division of Cardiology at Children's National Health System. She is Director of the Fetal Heart Program and Critical Care Delivery Program, Director of the Advanced Cardiac Imaging Fellowship, and Co-director of the Cardiac Neurodevelopmental Outcome Program. Under her leadership, the Fetal Heart Program treats each fetus as an individual patient, and specialized care begins before birth. With her vision, she expanded the program to include the Washington, DC, region’s only Early Fetal Cardiac Imaging Program, where we can detect heart abnormalities in high-risk pregnancies in the first trimester, as early as 12 weeks gestation.
Dr. Donofrio specializes in fetal diagnosis and in-utero management of congenital heart disease, first trimester fetal cardiac imaging, fetal echocardiography, pediatric transthoracic and transesophageal echocardiography, delivery room management and transitional care for complex disease, complex congenital heart disease management, and neurodevelopmental outcome assessment of children with congenital heart disease. She also plays a leadership role in our echocardiography laboratory and serves as director of the Advanced Cardiac Imaging fellowship.
Dr. Donofrio joined the staff at Children’s National after spending nine years at the Virginia Commonwealth University School of Medicine, directing the echocardiography laboratory. She completed her cardiology fellowship training at Children’s Hospital of Philadelphia and performed advanced training in fetal echocardiography at Yale University. Dr. Donofrio is a fellow of the American College of Cardiology, American Academy of Pediatrics, and American Society of Echocardiography. She is a member of the American Pediatric Society and the Society for Pediatric Research.
Her research has focused on autoregulation of cerebral blood flow in fetuses with congenital heart disease and the effects the circulation has on neurodevelopmental outcome in congenital heart disease patients. She also has developed care protocols for delivery room management of neonates diagnosed with complex congenital heart disease in-utero. She is a national expert in the areas of fetal cardiology, echocardiology, and pediatric cardiology. Dr. Donofrio is on several journal editorial boards, research committees, and has published over 60 papers and abstracts, including the first published Guidelines for the Diagnosis and Treatment of Fetal Cardiac Disease.
Dr. Donofrio see patients at the Sheikh Zayed Campus for Advanced Children's Medicine and Children's Outpatient Centers. She also collaborates with Maternal-Fetal Medicine Specialists in the community seeing families with them in their local offices.
Dr. Donofrio is married and has two children. She grew up in Delaware and currently resides in Northern Virginia. Her interests include theater and music.
Research & Publications
Research & Publications
Diagnosis and Treatment of Fetal Cardiac Disease: A Scientific Statement from the American Heart Association.
Early Fetal Echocardiography: Congenital Heart Disease Detection and Diagnostic Accuracy in the Hands of an Experienced Fetal Cardiology Program.
(2014) Prenatal Diagnosis
Specialized Delivery Room Planning in Fetuses with Critical Congenital Heart Disease.
(2013) American Journal of Cardiology
Predictors of Repair and Outcome in Prenatally Diagnosed Atrioventricular Septal Defects.
(2013) Journal of the American Society of Echocardiography
Impact of Congenital Heart Disease on Fetal Brain Development and Injury.
(2011) Current Opinion in Pediatrics
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