Children's Research Institute’s investigators have access to state-of-the-art centralized areas of technology and expertise. Some of these core facilities are run as a fee for service facility and others are based on collaborative scientific relationships. Please contact the Core Director to access and learn more about the services provided.
Cellular Neuroscience Imaging
The Cellular Neuroscience Imaging Core assists investigators with a broad array of imaging tools for neuroscience analysis including stereo dissection microscopes, electron microscopy, wide-field fluorescence microscopy, unbiased stereology, and time-lapse multiphoton microscopy. A major effort of the Core is advisory services to investigators to help plan and carry out experiments. As such, the Core staff spends considerable time training new investigators and troubleshooting.
Director: Jyoti Jaiswal, PhD
Fluorescence Activated Cell Sorting (FACS)
The FACS Core facility currently has a BDInFlux cell sorter, 4 cell analyzers, MACSQuant analyzer, BD FACSCalibur, Amnis Imagestream X and BD FACSCanto II to serve a large diverse group of laboratory investigators and clinicians at Children’s National Health System.
Director: Chris Lazarski, PhD
The Center for Genetic Medicine Research and the Department of Integrated Systems Biology host a series of regional and national core facilities. The goal of these core facilities is to facilitate research across the institute as well as external laboratories, through applications of specialized technologies and expertise to investigators’ projects. The core houses state-of-the-art equipment purchased through institutional funds, philanthropic donations, and research grants, totaling more than $10 million. Providing other investigators easy access to these facilities and equipment is an important value shared by the faculty.
- DNA and mRNA technologies: Eric Hoffman, PhD; Susan Knoblach, PhD
- Proteomics technologies: Kristy Brown, PhD; Susan Knoblach, PhD
- Microscopy: Jyoti Jaiswal, PhD
- Pre-clinical murine drug testing: Kanneboyina Nagaraju, DVM, PhD
- Bioinformatics: Eric Hoffman, PhD; Susan Knoblach, PhD; Zuyi Wang, PhD
Investigational Drug Service:
The Investigational Drug Service (IDS) is a research pharmacy charged with the management of research medications used in clinical drug trials, as well as the oversight of medication use in drug trials conducted throughout Children’s National. The staff provides a comprehensive scope of services and is available for consultations to investigators throughout all phases of the clinical trial process.
Manager: Sarah Donaghan, PharmD, BCOP
The animal care program at Children’s National is fully accredited by the AAALAC. The primary function of the RAF is to assist faculty, trainees, and staff in upholding organizational commitment to treat animals in a humane way, according to the highest ethical and scientific standards.
Director: JanNean Williams